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Long touted as beneficial for heart health, high-density lipoprotein (HDL) is more complicated than experts once thought. Some forms of HDL grab cholesterol from the bloodstream and other tissues and transport it to the liver, where it's recycled or disposed, but other types are neutral or perform the opposite action. Most drugs that raise HDL don't seem to prevent heart disease, and very high HDL levels may even be linked to a higher risk.

Hybrid exercise training combines heart-pumping aerobic action with muscle-strengthening moves in the same exercise session. The strategy has the advantage of meeting two key goals of the federal Physical Activity Guidelines in one fell swoop. And it also appears to be one of the best—and most time-efficient—ways for people who are overweight to lower their risk of cardiovascular-related risk factors. Strong muscles boost a person's basal metabolic rate—the amount of energy the body needs to keep working during rest. That improves weight-loss efforts by ramping up the number of calories burned.

People with high triglyceride levels may be candidates for icosapent ethyl (Vascepa), a drug made from highly purified fish oil. It lowers triglycerides and, when taken with a statin, lowers the risk of heart attack, stroke, and death from cardiac causes.

An analysis shows less than 7% of adults in the US meet the criteria for optimal cardiometabolic health. Taking small steps to help control and improve key risk factors can reduce the odds of a heart attack or stroke.

Seven factors appear to account for most first heart attacks in people ages 55 and younger: diabetes, depression, high blood pressure, current smoking, family history of early heart attack, low household income, and high cholesterol.

Two important types of fat in the body are white fat and brown fat. White fat is located in the chest, abdomen, and upper legs; too much of it constitutes obesity. Its function is to provide insulation against the cold, store fats derived from food, and continually release small amounts of the fats to be converted into energy. Brown fat is found in small amounts in the neck, shoulders, chest, and abdomen. Its main function is to burn the fat it stores, creating heat that keeps the body warm.

A traditional Nordic diet featuring whole grains, berries, canola oil, fish, and low-fat dairy may improve heart-related risk factors, even if people following the diet don't lose weight.

Some people decide to adopt a vegan diet because of concerns about the health effects of eating animal products; for others it's more about concern for animal welfare and the environment. Regardless of the motivation, those who want to make this change should anticipate potential pitfalls and be aware of issues specific to vegan eating.

A study published online Feb. 16, 2022, by the European Heart Journal suggests that the prevalence of statin intolerance is much lower than commonly cited. Instead of 50%, the study found that prevalence is 6% to 10%.