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Cholesterol Archive

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Know the facts about fats

You need adequate amounts of good dietary fat.


ÌýImage: © JulijaDmitrijeva/Getty Images

Low fat? No fat? Try more fat. Dietary fats are essential for maintaining good overall health, especially as you age. "Your body needs a regular intake of fat," says Vasanti Malik, a research scientist with the Department of Nutrition at Harvard's T.H. Chan School of Public Health. "Fat helps give your body energy, protects your organs, supports cell growth, keeps cholesterol and blood pressure under control, and helps your body absorb vital nutrients. When you focus too much on cutting out all fat, you can actually deprive your body of what it needs most."

Two types of fats

To understand the role fats play in a healthy diet, you have to look closer at the two types of dietary fats: saturated and unsaturated. (A third kind, trans fats, have been all but eliminated from U.S. foods.)

Why nuts may be good for your heart

Research we're watching

Eating nuts even just a couple of times a week is linked to a lower risk of dying from heart disease, a new study suggests.

The study included 39,000 women who filled out dietary questionnaires at the start of the study and again about 10 years later. During the follow-up, which lasted an average of 19 years, nearly 1,000 of the women died of cardiovascular disease.

"Green" Mediterranean diet: Better than the original?

Research we're watching

Widely considered the healthiest diet for your heart, the Mediterranean diet is rich in plant-based foods and features only small amounts of meat and dairy products. But a variation that includes more green plant foods may be even better for you, a small study suggests.

The study included 294 sedentary, moderately obese people whom researchers randomly divided into three groups. Each received different dietary advice: a standard healthy diet, a low-calorie Mediterranean diet, or a "green" Mediterranean diet. Both Mediterranean diet groups included about a quarter-cup of walnuts daily, and poultry and fish replaced beef and lamb.

Fears about statin side effects: Often unfounded?

A novel study suggests that the "nocebo effect" could be why some people believe they cannot tolerate statins.

Are you hesitant to fill your statin prescription because you're worried the drug will cause muscle aches and other side effects? Although you're far from alone (see "A royal pain?"), the reality is that all drugs have side effects, and statins aren't worse than other drugs. And fears about statin side effects may be depriving people of a potentially lifesaving medication.

The nocebo effect � the flip side of the well-known placebo effect � occurs when people experience negative effects from a drug, placebo, or other treatment based on an expectation of harm. Because of the widespread belief that statins cause muscle aches, statins have been suspected of triggering a strong nocebo effect. A recent study confirmed this observation (see "A study to assess statin side effects").

Treating heart attacks: Changes from Eisenhower’s era to the present day

In the 1950s, doctors offered mainly morphine and bed rest � a far cry from the many procedures and medications provided today.

During a round of golf one autumn afternoon in 1955, President Dwight Eisenhower experienced what he assumed was indigestion. After he awoke at 2 a.m. the following morning with severe chest pain, his personal physician administered several shots of morphine. It wasn't until 1 p.m. that afternoon that an electrocardiogram revealed that the president had experienced a heart attack.

Cardiologist Dr. Thomas Lee, professor of medicine at Harvard Medical School, detailed Eisenhower's experience in the Oct. 29, 2020, issue of The New England Journal of Medicine. His piece focuses mainly on how Eisenhower's cardiologist, Paul Dudley White, communicated the event to the public. As Dr. Lee wrote, "Heart attacks became less mysterious and frightening to millions of Americans that day."

Can you supercharge the Mediterranean diet?

News briefs

A Mediterranean-style diet is rich in vegetables, legumes, fruits, whole grains, nuts, seeds, poultry, fish, and olive oil, and it's associated with lower risks for heart disease and diabetes. And a "greener" version of the eating style might be even more effective, according to a small, randomized study published online Nov. 23, 2020, by the journal Heart. Researchers � some from Harvard � recruited about 300 sedentary, middle-aged people (mostly men) with high cholesterol or abdominal obesity and divided them into three groups. One received guidance for exercise and a healthy diet; another received exercise guidance and was assigned to eat a calorie-restricted Mediterranean diet; and one group received exercise guidance and was assigned to eat a "greener" calorie-restricted Mediterranean diet with less animal-based and more plant-based proteins (including walnuts and a type of duckweed � an aquatic plant), plus lots of green tea. After six months, people on the "green" diet had lost more weight and inches around their middles, and had bigger drops in cholesterol, than people in the other two groups. "Green" dieters also had steeper declines in insulin resistance, inflammation markers, and diastolic blood pressure (the lower number in the measurement), compared with the other two groups.

Image: © Lilechka75/Getty Images

Statin side effect could be due to the "nocebo" effect

In the journals

People who are worried about statins because of possible side effects may experience what's called the "nocebo effect" when they try taking the drugs. This is the opposite of the placebo effect; with the nocebo effect, people who have negative expectations about medicine or a treatment experience harmful symptoms they otherwise wouldn't have.

Researchers recruited 60 people, average age 66, who had previously stopped statins after two weeks because of side effects. For one month each, they took 20 milligrams of atorvastatin (Lipitor), a placebo, or no pill. They then continued this monthly rotation for a year without knowing which pill was which.

Bad habits come in pairs

Your partner's flawed health behaviors may be harming your heart.

It's been said that the longer couples stay together the more they look alike. As it turns out, the resemblance may be more than skin-deep. A study published online Oct. 26, 2020, by JAMA Network Open found that couples' health behavior and heart disease risk factors also look alike � for better or worse.

"We know, even from personal experience, that couples share similar behaviors that can affect health, but it was surprising to find the high levels of shared unhealthy behaviors within couples," says the study's lead author, Dov Shiffman, a senior scientific fellow at the medical testing company Quest Diagnostics.

Gut check: How the microbiome may mediate heart health

Your cholesterol and other factors linked to cardiovascular health may be influenced by the bacteria in your belly.

The roughly 38 trillion bacteria that dwell deep within your intestines perform many important tasks. Collectively known as the gut microbiota, these microbes help digest food, metabolize medications, and protect you from infectious organisms.

In many ways, your gut microbiota � which weighs about half a pound in total � functions somewhat like a distinct organ in your body. Just as you have a unique genome, you also have a unique gut microbiome, consisting of some eight million genes that control your microbiota. Scientists are still learning how the composition and diversity of the gut microbiome influence the health of the cardiovascular system.

Get FITT to better fight heart disease

If you've been diagnosed with heart disease, the FITT approach can reduce your risk for heart attack and stroke.

About half of all Americans have at least one of the key risk factors for heart disease, such as high cholesterol, high blood pressure, and excess weight.

You can address those risks with a heart-healthy diet and medications to lower blood pressure and cholesterol levels. But perhaps the biggest boost you can give your heart is regular aerobic exercise.

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